ODCs

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1 OMIM reference -
1 associated gene
14 signs/symptoms

PROTEIN INTERACTIONS: 1

2 OMIM references -
3 associated genes
No signs/symptoms info

Autosomal dominant osteosclerosis, Worth type

Persistent hyperplastic primary vitreous


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	LRP5	(0.63)	NDP

Citations in the biomedical literature:

Autosomal dominant osteosclerosis, Worth type		Persistent hyperplastic primary vitreous
	Synonym(s): - Endosteal hyperostosis, Worth type - Worth syndrome		Synonym(s): - PFVS - PHPV - Persistent fetal vasculature syndrome

	Classification (Orphanet): - Rare bone disease - Rare developmental defect during embryogenesis - Rare genetic disease		Classification (Orphanet): - Rare eye disease - Rare genetic disease

	Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -		Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -

	Epidemiological data: Class of prevalence: - Average age onset: - Average age of death: - Type of inheritance: autosomal dominant		Epidemiological data: Class of prevalence: unknown Average age onset: neonatal/infancy Average age of death: - Type of inheritance: autosomal dominant

	External references: 1 OMIM reference - No MeSH references		External references: 2 OMIM references - 1 MeSH reference: D054514

Autosomal dominant osteosclerosis, Worth type
	Very frequent - Anomalies of the ribs - Autosomal dominant inheritance - Clavicle absent / abnormal - Cortical anomaly / thick bone cortical layer - Dense / thickened skull / calvarium / cranial / facial hyperostosis - Enlarged diaphysis / diaphyses - Osteosclerosis / osteopetrosis / bone condensation - Palate exostoses / torus palatinus Frequent - Abnormal vertebral size / shape - Enlargment of jaw / large jaw Occasional - Facial palsy - Nystagmus - Prognathism / prognathia - Sensorineural deafness / hearing loss
Persistent hyperplastic primary vitreous
(no data available)